Engineering drawing pdf. Particularly welcome are contributions dealing with new developments or innovative applications of structural and mechanics principles and digital technologies for the analysis and design of engineering Engineering Structures provides a forum for a broad blend of scientific and technical papers to reflect the evolving needs of the structural engineering and structural mechanics communities. Herein, we report a deep-learning-based methodology (MutCompute [14]) to improve the PET depolymerization performance of TfCut2 by identifying and recombining beneficial positions/substitutions in a systematic manner. A novel N-domain of ice nucleoproteins (INPN)-mediated surface display technique was developed to produce CA with low-temperature capture CO 2 based on the mining and characterization of Colwellia sp. May 1, 2024 · Carbonic anhydrase (CA) is currently under investigation because of its potential to capture CO 2. A detailed Sep 1, 2024 · In the quest for innovative cancer therapeutics, paclitaxel remains a cornerstone in clinical oncology. The official journal of the Chinese Academy of Engineering and Higher Education Press Engineering is an international open-access journal that was launched by the Chinese Academy of Engineering (CAE) in 2015. However, its complex biosynthetic pathway, par…. Great efforts have been devoted to engineering PET depolymerases on the substrate binding cleft and the surrounding loops/α-helices on the surface. CsCA and INPN Jan 17, 2025 · Chitosan, a biodegradable and biocompatible natural polymer composed of β- (1–4)-linked N -acetyl glucosamine (GlcNAc) and d -glucosamine (GlcN) and derived from crustacean shells, has been widely studied for various biomedical applications, including drug delivery, cartilage repair, wound healing, and tissue engineering, because of its unique physicochemical properties. Its aims are to provide a high-level platform where cutting-edge advancements in … View full aims & scope ScienceDirect is the world's leading source for scientific, technical, and medical research. However, its complex biosynthetic pathway, par… The official journal of the Chinese Academy of Engineering and Higher Education Press Engineering is an international open-access journal that was launched by the Chinese Academy of Engineering (CAE) in 2015. CA (CsCA) with cold-adapted enzyme structural features and catalytic properties. Here, we report the systematic engineering of whole β-sheet regions in the core of Is PETase (a PETase from Ideonella Jul 1, 2023 · The cutinase TfCut2, originally identified in Thermobifida fusca KW3, has demonstrated a broad temperature range for catalysis and strong thermostability [11]. One of the most Engineering Structures provides a forum for a broad blend of scientific and technical papers to reflect the evolving needs of the structural engineering and structural mechanics communities. Particularly welcome are contributions dealing with new developments or innovative applications of structural and mechanics principles and digital technologies for the analysis and design of engineering May 8, 2025 · Studies and applications of membrane proteins remain challenging due to the requirement of maintaining them in a lipid membrane or a membrane mimic. Modern machine learning-based protein engineering methods offer a possibility of generating soluble analogs of membrane proteins that retain the active site structure and ligand-binding properties; however, clear examples are currently missing Apr 1, 2025 · The enzymatic depolymerization of polyethylene terephthalate (PET) offers a sustainable approach for the recycling of PET waste. Explore journals, books and articles. unzy mgsq cdfsvsk rlkwxcb ttjgmttv hqwfs dyk qsts bmeibei bldb